6RAV

Complement factor B protease domain in complex with the reversible inhibitor 4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic acid

This is a non-PDB format compatible entry.

Replaces:  6QSV

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	AAA, BBB	Complement factor B	polymer	291	32955.9	2	UniProt (P00751) Pfam (PF00089) In PDB	Homo sapiens (Human)	C3/C5 convertase,Glycine-rich beta glycoprotein,GBG,PBF2,Properdin factor B
2	AAA, BBB	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)
3	AAA, BBB	4-[(2~{S},4~{S})-4-ethoxy-1-[(5-methoxy-7-methyl-1~{H}-indol-4-yl)methyl]piperidin-2-yl]benzoic acid	non-polymer		422.5	2	Chemie (JGQ)
4	BBB	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
5		water	water		18.0	366	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	65911.8
Non-Polymers*	Number of molecules	9
	Total formula weight	1456.2
All*	Total formula weight	67367.9

*Water molecules are not included.