6R7N
Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome
Summary for 6R7N
Entry DOI | 10.2210/pdb6r7n/pdb |
EMDB information | 4744 |
Descriptor | COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, ZINC ION, ... (11 entities in total) |
Functional Keywords | cullin-ring e3 ligases (crls) cop9 signalosome (csn) deneddylation vhl tumour suppressor substrate receptor, ligase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 10 |
Total formula weight | 367024.37 |
Authors | Faull, S.V.,Lau, A.M.C.,Martens, C.,Ahdash, Z.,Yebenes, H.,Schmidt, C.,Beuron, F.,Cronin, N.B.,Morris, E.P.,Politis, A. (deposition date: 2019-03-29, release date: 2019-08-28, Last modification date: 2024-05-22) |
Primary citation | Faull, S.V.,Lau, A.M.C.,Martens, C.,Ahdash, Z.,Hansen, K.,Yebenes, H.,Schmidt, C.,Beuron, F.,Cronin, N.B.,Morris, E.P.,Politis, A. Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome. Nat Commun, 10:3814-3814, 2019 Cited by PubMed: 31444342DOI: 10.1038/s41467-019-11772-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (6.5 Å) |
Structure validation
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