6R4S
Crystal structure of the Pri1 subunit of human primase bound to ATP
Summary for 6R4S
Entry DOI | 10.2210/pdb6r4s/pdb |
Related | 6R4T 6R4U 6R5D 6R5E 6RB4 |
Descriptor | DNA primase small subunit, ZINC ION, MANGANESE (II) ION, ... (5 entities in total) |
Functional Keywords | primase, dna-dependent rna polymerase, atp, priming, replication |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 98805.96 |
Authors | Kilkenny, M.L.,Pellegrini, L. (deposition date: 2019-03-24, release date: 2019-09-11, Last modification date: 2024-01-24) |
Primary citation | Holzer, S.,Rzechorzek, N.J.,Short, I.R.,Jenkyn-Bedford, M.,Pellegrini, L.,Kilkenny, M.L. Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine. Acs Chem.Biol., 14:1904-1912, 2019 Cited by PubMed: 31479243DOI: 10.1021/acschembio.9b00367 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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