6R4L

Crystal structure of S. cerevisia Niemann-Pick type C protein NCR1

6R4L の概要

• エントリーDOI: 10.2210/pdb6r4l/pdb
• 分子名称: NPC intracellular cholesterol transporter 1-related protein 1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ERGOSTEROL, ... (4 entities in total)
• 機能のキーワード: vacuole, ergosterol, lipid transport, membrane protein
• 由来する生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 137503.99

構造登録者

Winkler, M.B.L.,Kidmose, R.T.,Pedersen, B.P. (登録日: 2019-03-22, 公開日: 2019-09-25, 最終更新日: 2024-01-24)

• 主引用文献: Winkler, M.B.L.,Kidmose, R.T.,Szomek, M.,Thaysen, K.,Rawson, S.,Muench, S.P.,Wustner, D.,Pedersen, B.P.; Structural Insight into Eukaryotic Sterol Transport through Niemann-Pick Type C Proteins.; Cell, 179:485-497.e18, 2019; PubMed: 31543266; DOI: 10.1016/j.cell.2019.08.038

実験手法

X-RAY DIFFRACTION (3.5 Å)