6R0B
T. cruzi FPPS in complex with 3-((4-(5-chlorobenzo[d]thiazol-2-yl)piperazin-1-yl)methyl)-1H-indol-5-ol
Summary for 6R0B
Entry DOI | 10.2210/pdb6r0b/pdb |
Descriptor | Farnesyl diphosphate synthase, 3-[[4-(5-chloranyl-1,3-benzothiazol-2-yl)piperazin-1-yl]methyl]-1~{H}-indol-5-ol, ZINC ION, ... (5 entities in total) |
Functional Keywords | farnesyl diphosphate synthase, sterol biosynthesis, farnesyl pyrophosphate, homodimer, transferase |
Biological source | Trypanosoma cruzi |
Total number of polymer chains | 1 |
Total formula weight | 42016.02 |
Authors | Petrick, J.K.,Muenzker, L.,Schleberger, C.,Jahnke, W. (deposition date: 2019-03-12, release date: 2020-04-01, Last modification date: 2024-02-07) |
Primary citation | Petrick, J.K.,Jahnke, W. Targeting farnesyl pyrophosphate synthase of Trypanosoma cruzi by fragment-based lead discovery Thesis, 2019 Cited by DOI: 10.17192/z2019.0501PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.612 Å) |
Structure validation
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