6R0A

T. cruzi FPPS in complex with 3-((4-(benzo[d]thiazol-2-yl)piperazin-1-yl)methyl)-1H-indol-5-ol

Summary for 6R0A

Entry DOI	10.2210/pdb6r0a/pdb
Descriptor	Farnesyl diphosphate synthase, 3-[[4-(1,3-benzothiazol-2-yl)piperazin-1-yl]methyl]-1~{H}-indol-5-ol, ACETATE ION, ... (6 entities in total)
Functional Keywords	farnesyl diphosphate synthase, sterol biosynthesis, farnesyl pyrophosphate, homodimer, transferase
Biological source	Trypanosoma cruzi
Total number of polymer chains	1
Total formula weight	42374.43
Authors	Petrick, J.K.,Muenzker, L.,Schleberger, C.,Jahnke, W. (deposition date: 2019-03-12, release date: 2020-04-01, Last modification date: 2024-02-07)
Primary citation	Petrick, J.K.,Jahnke, W. Targeting farnesyl pyrophosphate synthase of Trypanosoma cruzi by fragment-based lead discovery Thesis, 2019 Cited by DOI: 10.17192/z2019.0501 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.32 Å)

Structure validation