6R09

T. cruzi FPPS in complex with 2-(4-((1H-indol-3-yl)methyl)piperazin-1-yl)benzo[d]thiazole

Summary for 6R09

Entry DOI	10.2210/pdb6r09/pdb
Descriptor	Farnesyl diphosphate synthase, 2-[4-(1~{H}-indol-3-ylmethyl)piperazin-1-yl]-1,3-benzothiazole, ZINC ION, ... (5 entities in total)
Functional Keywords	farnesyl diphosphate synthase, sterol biosynthesis, farnesyl pyrophosphate, homodimer, transferase
Biological source	Trypanosoma cruzi
Total number of polymer chains	1
Total formula weight	42030.98
Authors	Petrick, J.K.,Muenzker, L.,Schleberger, C.,Jahnke, W. (deposition date: 2019-03-12, release date: 2020-04-01, Last modification date: 2024-02-07)
Primary citation	Petrick, J.K.,Jahnke, W. Targeting farnesyl pyrophosphate synthase of Trypanosoma cruzi by fragment-based lead discovery Thesis, 2019 Cited by DOI: 10.17192/z2019.0501 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.28 Å)

Structure validation