6QYA
Crystal structure of Enteroccocus faecalis thymidylate synthase (EfTS) in complex with dUMP
Summary for 6QYA
| Entry DOI | 10.2210/pdb6qya/pdb |
| Related | 6QXG 6QXH 6QXS |
| Descriptor | Thymidylate synthase, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 1,2-ETHANEDIOL, ... (8 entities in total) |
| Functional Keywords | enteroccocus faecalis thymidylate synthase, efts, folate pathway, substrate, dump, transferase |
| Biological source | Enterococcus faecalis More |
| Total number of polymer chains | 4 |
| Total formula weight | 148297.77 |
| Authors | Pozzi, C.,Mangani, M. (deposition date: 2019-03-08, release date: 2019-04-10, Last modification date: 2024-01-24) |
| Primary citation | Pozzi, C.,Ferrari, S.,Luciani, R.,Tassone, G.,Costi, M.P.,Mangani, S. Structural Comparison ofEnterococcus faecalisand Human Thymidylate Synthase Complexes with the Substrate dUMP and Its Analogue FdUMP Provides Hints about Enzyme Conformational Variabilities. Molecules, 24:-, 2019 Cited by PubMed: 30935102DOI: 10.3390/molecules24071257 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.76 Å) |
Structure validation
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