6QYA
Crystal structure of Enteroccocus faecalis thymidylate synthase (EfTS) in complex with dUMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Thymidylate synthase | polymer | 315 | 36402.0 | 2 | UniProt (Q834R3) Pfam (PF00303) | Enterococcus faecalis | TSase |
| 2 | B, D (B, D) | Thymidylate synthase | polymer | 315 | 36462.1 | 2 | UniProt (Q834R3) Pfam (PF00303) | Enterococcus faecalis | TSase |
| 3 | E, P (A, C) | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | non-polymer | 308.2 | 2 | Chemie (UMP) | |||
| 4 | F, G, K, L, M... (A, B, C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 11 | Chemie (EDO) | |||
| 5 | H, R (B, D) | N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid | non-polymer | 473.4 | 2 | Chemie (FFO) | |||
| 6 | I, J, S (B, D) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 7 | W (D) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 8 | AA, X, Y, Z (D, A, B, C) | water | water | 18.0 | 1459 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 145728.1 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 2569.6 | |
| All* | Total formula weight | 148297.8 |
