6QXF

Cas1-Cas2-Csn2-DNA complex from the Type II-A CRISPR-Cas system

Summary for 6QXF

Entry DOI	10.2210/pdb6qxf/pdb
EMDB information	4668
Descriptor	CRISPR-associated protein Csn2, CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, ... (6 entities in total)
Functional Keywords	crispr, cas, dna binding, nuclease, adaptation, spacer acquisition, dna binding protein, protein complex, protein-dna complex, calcium, metal-binding, antiviral
Biological source	Streptococcus thermophilus More
Total number of polymer chains	22
Total formula weight	556567.41
Authors	Wilkinson, M.,Drabavicius, G.,Silanskas, A.,Gasiunas, G.,Siksnys, V.,Wigley, D.B. (deposition date: 2019-03-07, release date: 2019-05-08, Last modification date: 2024-05-15)
Primary citation	Wilkinson, M.,Drabavicius, G.,Silanskas, A.,Gasiunas, G.,Siksnys, V.,Wigley, D.B. Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System. Mol.Cell, 75:90-101.e5, 2019 Cited by PubMed: 31080012 DOI: 10.1016/j.molcel.2019.04.020 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.6 Å)

Structure validation