6QWI

Structure of beta-glucosidase A from Paenibacillus polymyxa complexed with multivalent inhibitors.

Summary for 6QWI

Entry DOI	10.2210/pdb6qwi/pdb
Descriptor	Beta-glucosidase A, (2~{S},3~{S},4~{R})-2-[[4-[4-(2-ethoxyethoxy)phenyl]-1,2,3-triazol-1-yl]methyl]pyrrolidine-3,4-diol (3 entities in total)
Functional Keywords	hydrolase, beta-glucosidase, glycosidase, carbohydrate, carbohydrate metabolism, polisaccharide degradation, complex, inhibitor
Biological source	Paenibacillus polymyxa
Total number of polymer chains	2
Total formula weight	103914.23
Authors	Jimenez-Ortega, E.,Sanz-Aparicio, J. (deposition date: 2019-03-05, release date: 2019-07-03, Last modification date: 2024-01-24)
Primary citation	Martinez-Bailen, M.,Jimenez-Ortega, E.,Carmona, A.T.,Robina, I.,Sanz-Aparicio, J.,Talens-Perales, D.,Polaina, J.,Matassini, C.,Cardona, F.,Moreno-Vargas, A.J. Structural basis of the inhibition of GH1 beta-glucosidases by multivalent pyrrolidine iminosugars. Bioorg.Chem., 89:103026-103026, 2019 Cited by PubMed: 31226649 DOI: 10.1016/j.bioorg.2019.103026 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.85 Å)

Structure validation