6QWA

Crystal structure of KPC-3 complexed with relebactam (16 hour soak)

Summary for 6QWA

Entry DOI	10.2210/pdb6qwa/pdb
Descriptor	Beta-lactamase, SULFATE ION, GLYCEROL, ... (7 entities in total)
Functional Keywords	inhibitor, relebactam, diazabicyclooctane, antibiotic resistance., antimicrobial protein
Biological source	Klebsiella pneumoniae
Total number of polymer chains	1
Total formula weight	31780.65
Authors	Tooke, C.L.,Hinchliffe, P.,Spencer, J. (deposition date: 2019-03-05, release date: 2019-08-21, Last modification date: 2024-01-24)
Primary citation	Tooke, C.L.,Hinchliffe, P.,Lang, P.A.,Mulholland, A.J.,Brem, J.,Schofield, C.J.,Spencer, J. Molecular Basis of Class A beta-Lactamase Inhibition by Relebactam. Antimicrob.Agents Chemother., 63:-, 2019 Cited by PubMed: 31383664 DOI: 10.1128/AAC.00564-19 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.06 Å)

Structure validation