6QUN

Crystal structure of AtGapC1 with the catalytic Cys149 irreversibly oxidized by H2O2 treatment

Summary for 6QUN

Entry DOI	10.2210/pdb6qun/pdb
Related	4Z0H
Descriptor	Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ... (4 entities in total)
Functional Keywords	rossman fold, nad binding, glycolytic process, oxidative stress, hydrogen peroxide, oxidoreductase
Biological source	Arabidopsis thaliana (Mouse-ear cress)
Total number of polymer chains	2
Total formula weight	75098.71
Authors	Fermani, S.,Zaffagnini, M.,Falini, G.,Trost, P. (deposition date: 2019-02-28, release date: 2019-12-04, Last modification date: 2024-01-24)
Primary citation	Zaffagnini, M.,Marchand, C.H.,Malferrari, M.,Murail, S.,Bonacchi, S.,Genovese, D.,Montalti, M.,Venturoli, G.,Falini, G.,Baaden, M.,Lemaire, S.D.,Fermani, S.,Trost, P. Glutathionylation primes soluble glyceraldehyde-3-phosphate dehydrogenase for late collapse into insoluble aggregates. Proc.Natl.Acad.Sci.USA, 116:26057-26065, 2019 Cited by PubMed: 31772010 DOI: 10.1073/pnas.1914484116 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation