6QS4
Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor.
Summary for 6QS4
Entry DOI | 10.2210/pdb6qs4/pdb |
EMDB information | 4621 4622 4623 4624 4625 4626 4627 |
Descriptor | Chaperone protein ClpB, casein, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... (4 entities in total) |
Functional Keywords | disaggregase, proteostasis, aaa, chaperone |
Biological source | Escherichia coli (strain ATCC 9637 / CCM 2024 / DSM 1116 / NCIMB 8666 / NRRL B-766 / W) More |
Total number of polymer chains | 7 |
Total formula weight | 581536.31 |
Authors | Deville, C.,Saibil, H.R. (deposition date: 2019-02-20, release date: 2019-07-03, Last modification date: 2024-05-15) |
Primary citation | Deville, C.,Franke, K.,Mogk, A.,Bukau, B.,Saibil, H.R. Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor. Cell Rep, 27:3433-3446.e4, 2019 Cited by PubMed: 31216466DOI: 10.1016/j.celrep.2019.05.075 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.2 Å) |
Structure validation
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