6QPC

Cryo-EM structure of calcium-bound mTMEM16F lipid scramblase in nanodisc

Summary for 6QPC

• Entry DOI: 10.2210/pdb6qpc/pdb
• EMDB information: 4613
• Descriptor: Anoctamin-6, CALCIUM ION, 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE (3 entities in total)
• Functional Keywords: lipid scrambles, tmem16, membrane protein
• Biological source: Mus musculus (house mouse)
• Total number of polymer chains: 2
• Total formula weight: 214029.22

Authors

Alvadia, C.,Lim, N.K.,Clerico Mosina, V.,Oostergetel, G.T.,Dutzler, R.,Paulino, C. (deposition date: 2019-02-13, release date: 2019-03-06, Last modification date: 2019-04-03)

• Primary citation: Alvadia, C.,Lim, N.K.,Clerico Mosina, V.,Oostergetel, G.T.,Dutzler, R.,Paulino, C.; Cryo-EM structures and functional characterization of the murine lipid scramblase TMEM16F.; Elife, 8:-, 2019; PubMed: 30785399; DOI: 10.7554/eLife.44365

Experimental method

ELECTRON MICROSCOPY (3.5 Å)