6QMB

Cryo-EM structure of calcium-bound nhTMEM16 lipid scramblase in nanodisc (closed state)

Summary for 6QMB

Entry DOI	10.2210/pdb6qmb/pdb
EMDB information	4594
Descriptor	Predicted protein, CALCIUM ION (2 entities in total)
Functional Keywords	membrane protein, lipid scrambles, tmem16
Biological source	Nectria haematococca
Total number of polymer chains	2
Total formula weight	166560.33
Authors	Kalienkova, V.,Clerico Mosina, V.,Bryner, L.,Oostergetel, G.T.,Dutzler, R.,Paulino, C. (deposition date: 2019-02-01, release date: 2019-03-06, Last modification date: 2019-12-18)
Primary citation	Kalienkova, V.,Clerico Mosina, V.,Bryner, L.,Oostergetel, G.T.,Dutzler, R.,Paulino, C. Stepwise activation mechanism of the scramblase nhTMEM16 revealed by cryo-EM. Elife, 8:-, 2019 Cited by PubMed: 30785398 DOI: 10.7554/eLife.44364 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.6 Å)

Structure validation