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6QIU

Crystal structure of 14-3-3 sigma in complex with Ataxin-1 Ser776 phosphopeptide

Summary for 6QIU
Entry DOI10.2210/pdb6qiu/pdb
Descriptor14-3-3 protein sigma, Ataxin-1 phosphopeptide, MAGNESIUM ION, ... (5 entities in total)
Functional Keywordsphosphoprotein binding anti-aggregation, protein binding
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight27959.10
Authors
Leysen, S.,Milroy, L.G.,Davis, J.M.,Brunsveld, L.,Ottmann, C. (deposition date: 2019-01-21, release date: 2020-05-13)
Primary citationLeysen, S.,Burnley, R.J.,Rodriguez, E.,Milroy, L.G.,Soini, L.,Adamski, C.J.,Davis, R.,Obsil, T.,Brunsveld, L.,Crabbe, T.,Zoghbi, H.Y.,Ottmann, C.,Davis, J.M.
Structural insights into the cytoplasmic chaperone effect of 14-3-3 proteins on Ataxin-1
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.802 Å)
Structure validation

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