6QG6
Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model D)
Summary for 6QG6
Entry DOI | 10.2210/pdb6qg6/pdb |
Related | 6QG0 6QG1 6QG2 6QG3 6QG5 |
EMDB information | 4543 4544 4545 4546 4547 4548 |
Descriptor | Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit gamma, ... (8 entities in total) |
Functional Keywords | integrated stress response, isr, translation, initiation factors, phosphorylation, eif2, eif2b, trnai, gef, heat domain, eif2 alpha |
Biological source | Saccharomyces cerevisiae (Baker's yeast) More |
Total number of polymer chains | 16 |
Total formula weight | 838127.37 |
Authors | Llacer, J.L.,Gordiyenko, Y.,Ramakrishnan, V. (deposition date: 2019-01-10, release date: 2019-06-26, Last modification date: 2019-12-18) |
Primary citation | Gordiyenko, Y.,Llacer, J.L.,Ramakrishnan, V. Structural basis for the inhibition of translation through eIF2 alpha phosphorylation. Nat Commun, 10:2640-2640, 2019 Cited by PubMed: 31201334DOI: 10.1038/s41467-019-10606-1 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.65 Å) |
Structure validation
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