6Q4M
Crystal structure of the O-GlcNAc transferase Asn648Tyr mutation
Summary for 6Q4M
Entry DOI | 10.2210/pdb6q4m/pdb |
Descriptor | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, (2S,3R,4R,5S,6R)-3-(acetylamino)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-thiopyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | glycosyltransferase, acceptor peptide, mutation, disease, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 81836.94 |
Authors | Gundogdu, M.,van Aalten, D.M.F. (deposition date: 2018-12-06, release date: 2019-12-25, Last modification date: 2024-05-15) |
Primary citation | Gundogdu, M.,van Aalten, D.M.F. Crystal structure of the O-GlcNAc transferase Asn648Tyr mutation To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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