6Q4M

Crystal structure of the O-GlcNAc transferase Asn648Tyr mutation

6Q4M の概要

• エントリーDOI: 10.2210/pdb6q4m/pdb
• 分子名称: UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, (2S,3R,4R,5S,6R)-3-(acetylamino)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-thiopyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate, PHOSPHATE ION, ... (4 entities in total)
• 機能のキーワード: glycosyltransferase, acceptor peptide, mutation, disease, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 81836.94

構造登録者

Gundogdu, M.,van Aalten, D.M.F. (登録日: 2018-12-06, 公開日: 2019-12-25, 最終更新日: 2024-05-15)

• 主引用文献: Gundogdu, M.,van Aalten, D.M.F.; Crystal structure of the O-GlcNAc transferase Asn648Tyr mutation; To Be Published,

実験手法

X-RAY DIFFRACTION (2.2 Å)