6Q2X

TEAD4 (216-434) COMPLEXED WITH YAP PEPTIDE (60-100) AND MYRISTOATE (COVALENTLY BOUND) AT 2.1A (P41212 CRYSTAL FORM)

6Q2X の概要

• エントリーDOI: 10.2210/pdb6q2x/pdb
• 分子名称: Transcriptional enhancer factor TEF-3, Transcriptional coactivator YAP1, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: other, transcription
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 30568.61

構造登録者

Kallen, J. (登録日: 2018-12-03, 公開日: 2019-07-03, 最終更新日: 2024-01-24)

• 主引用文献: Furet, P.,Salem, B.,Mesrouze, Y.,Schmelzle, T.,Lewis, I.,Kallen, J.,Chene, P.; Structure-based design of potent linear peptide inhibitors of the YAP-TEAD protein-protein interaction derived from the YAP omega-loop sequence.; Bioorg.Med.Chem.Lett., 29:2316-2319, 2019; PubMed: 31235263; DOI: 10.1016/j.bmcl.2019.06.022

実験手法

X-RAY DIFFRACTION (2.1 Å)