6Q2Q

Crystal structure of mouse viperin bound to uridine triphosphate and S-adenosylhomocysteine

Summary for 6Q2Q

• Entry DOI: 10.2210/pdb6q2q/pdb
• Descriptor: Radical S-adenosyl methionine domain-containing protein 2, IRON/SULFUR CLUSTER, S-ADENOSYL-L-HOMOCYSTEINE, ... (7 entities in total)
• Functional Keywords: interferon stimulated gene, radical s-adenosylmethionine enzyme, iron sulfur cluster, immune system
• Biological source: Mus musculus (Mouse)
• Total number of polymer chains: 2
• Total formula weight: 76253.93

Authors

Fenwick, M.K.,Dong, M.,Lin, H.,Ealick, S.E. (deposition date: 2019-08-08, release date: 2020-01-22, Last modification date: 2023-10-11)

• Primary citation: Fenwick, M.K.,Su, D.,Dong, M.,Lin, H.,Ealick, S.E.; Structural Basis of the Substrate Selectivity of Viperin.; Biochemistry, 59:652-662, 2020; PubMed: 31917549; DOI: 10.1021/acs.biochem.9b00741

Experimental method

X-RAY DIFFRACTION (1.892 Å)