6Q0K

Structure of a MAPK pathway complex

Summary for 6Q0K

• Entry DOI: 10.2210/pdb6q0k/pdb
• EMDB information: 20551
• Descriptor: Serine/threonine-protein kinase B-raf, 14-3-3 protein zeta/delta (2 entities in total)
• Functional Keywords: transferase, signaling protein-transferase complex, signaling protein/transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 234199.81

Authors

Park, E.,Rawson, S.,Jeon, H.,Eck, M.J. (deposition date: 2019-08-01, release date: 2019-10-09, Last modification date: 2020-04-22)

• Primary citation: Park, E.,Rawson, S.,Li, K.,Kim, B.W.,Ficarro, S.B.,Pino, G.G.,Sharif, H.,Marto, J.A.,Jeon, H.,Eck, M.J.; Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes.; Nature, 575:545-550, 2019; PubMed: 31581174; DOI: 10.1038/s41586-019-1660-y

Experimental method

ELECTRON MICROSCOPY (6.8 Å)