6PZ9
Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and repaglinide
Summary for 6PZ9
Entry DOI | 10.2210/pdb6pz9/pdb |
EMDB information | 20528 20530 20533 20534 20535 |
Descriptor | ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11, Repaglinide, ... (4 entities in total) |
Functional Keywords | katp, sur1, rpg, membrane protein |
Biological source | Cricetus cricetus (Black-bellied hamster) More |
Total number of polymer chains | 2 |
Total formula weight | 221939.06 |
Authors | Shyng, S.L.,Yoshioka, C.,Martin, G.M.,Sung, M.W. (deposition date: 2019-07-31, release date: 2019-08-14, Last modification date: 2024-03-20) |
Primary citation | Martin, G.M.,Sung, M.W.,Yang, Z.,Innes, L.M.,Kandasamy, B.,David, L.L.,Yoshioka, C.,Shyng, S.L. Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM. Elife, 8:-, 2019 Cited by PubMed: 31343405DOI: 10.7554/eLife.46417 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.65 Å) |
Structure validation
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