6PY8

Crystal structure of the RBPJ-NOTCH1-NRARP ternary complex bound to DNA

6PY8 の概要

• エントリーDOI: 10.2210/pdb6py8/pdb
• 分子名称: Notch-regulated ankyrin repeat-containing protein, DNA, Recombining binding protein suppressor of hairless, ... (5 entities in total)
• 機能のキーワード: notch1, nrarp, rbpj, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 226373.81

構造登録者

Jarrett, S.M.,Seegar, T.C.M.,Blacklow, S.C. (登録日: 2019-07-29, 公開日: 2019-08-14, 最終更新日: 2023-10-11)

• 主引用文献: Jarrett, S.M.,Seegar, T.C.M.,Andrews, M.,Adelmant, G.,Marto, J.A.,Aster, J.C.,Blacklow, S.C.; Extension of the Notch intracellular domain ankyrin repeat stack by NRARP promotes feedback inhibition of Notch signaling.; Sci.Signal., 12:-, 2019; PubMed: 31690634; DOI: 10.1126/scisignal.aay2369

実験手法

X-RAY DIFFRACTION (3.75 Å)