6PXF

Structure of human Cathepsin K with an ectosteric inhibitor at 1.85 Angstrom resolution

Summary for 6PXF

• Entry DOI: 10.2210/pdb6pxf/pdb
• Related: 6ASH
• Descriptor: Cathepsin K, 1,6,6-trimethyl-10,11-dioxo-6,7,8,9,10,11-hexahydrophenanthro[1,2-b]furan-2-sulfonic acid (3 entities in total)
• Functional Keywords: cathepsin k, exosite, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 25005.11

Authors

Law, S.,Aguda, A.H.,Nguyen, N.T.,Brayer, G.D.,Bromme, D. (deposition date: 2019-07-25, release date: 2020-07-29, Last modification date: 2023-10-11)

• Primary citation: Law, S.,Aguda, A.H.,Nguyen, N.T.,Brayer, G.D.,Bromme, D.; Structure of human Cathepsin K with an ectosteric inhibitor at 1.85 Angstrom resolution; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.85 Å)