6PXF
Structure of human Cathepsin K with an ectosteric inhibitor at 1.85 Angstrom resolution
Summary for 6PXF
Entry DOI | 10.2210/pdb6pxf/pdb |
Related | 6ASH |
Descriptor | Cathepsin K, 1,6,6-trimethyl-10,11-dioxo-6,7,8,9,10,11-hexahydrophenanthro[1,2-b]furan-2-sulfonic acid (3 entities in total) |
Functional Keywords | cathepsin k, exosite, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 25005.11 |
Authors | Law, S.,Aguda, A.H.,Nguyen, N.T.,Brayer, G.D.,Bromme, D. (deposition date: 2019-07-25, release date: 2020-07-29, Last modification date: 2023-10-11) |
Primary citation | Law, S.,Aguda, A.H.,Nguyen, N.T.,Brayer, G.D.,Bromme, D. Structure of human Cathepsin K with an ectosteric inhibitor at 1.85 Angstrom resolution To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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