6PWM

ADC-7 in complex with Beta-lactam antibiotic ceftazidime

Summary for 6PWM

Entry DOI	10.2210/pdb6pwm/pdb
Descriptor	Beta-lactamase, ACYLATED CEFTAZIDIME, GLYCINE, ... (4 entities in total)
Functional Keywords	substrate, beta-lactamase, antibiotic, adc-7., hydrolase
Biological source	Acinetobacter baumannii
Total number of polymer chains	4
Total formula weight	165187.02
Authors	Curtis, B.C.,Powers, R.A.,Wallar, B.J. (deposition date: 2019-07-23, release date: 2020-10-21, Last modification date: 2023-10-11)
Primary citation	Curtis, B.N.,Smolen, K.A.,Barlow, S.J.,Caselli, E.,Prati, F.,Taracila, M.A.,Bonomo, R.A.,Wallar, B.J.,Powers, R.A. Structural Insights into Inhibition of the Acinetobacter-Derived Cephalosporinase ADC-7 by Ceftazidime and Its Boronic Acid Transition State Analog. Antimicrob.Agents Chemother., 64:-, 2020 Cited by PubMed: 32988830 DOI: 10.1128/AAC.01183-20 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation