6PMD
Structure of ClpP from Staphylococcus aureus in complex with Acyldepsipeptide
Summary for 6PMD
Entry DOI | 10.2210/pdb6pmd/pdb |
Related | 5VZ2 5W18 6PKA |
Related PRD ID | PRD_002357 |
Descriptor | ATP-dependent Clp protease proteolytic subunit, SHV-WFP-SER-PRO-YCP-ALA-MP8 Acyldepsipeptide, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total) |
Functional Keywords | clpp adep, antibiotic, hydrolase-antibiotic complex, hydrolase/antibiotic |
Biological source | Staphylococcus aureus (strain NCTC 8325) More |
Total number of polymer chains | 25 |
Total formula weight | 326861.87 |
Authors | Griffith, E.C.,Lee, R.E. (deposition date: 2019-07-01, release date: 2019-11-06, Last modification date: 2023-11-15) |
Primary citation | Griffith, E.C.,Zhao, Y.,Singh, A.P.,Conlon, B.P.,Tangallapally, R.,Shadrick, W.R.,Liu, J.,Wallace, M.J.,Yang, L.,Elmore, J.M.,Li, Y.,Zheng, Z.,Miller, D.J.,Cheramie, M.N.,Lee, R.B.,LaFleur, M.D.,Lewis, K.,Lee, R.E. Ureadepsipeptides as ClpP Activators. Acs Infect Dis., 5:1915-1925, 2019 Cited by PubMed: 31588734DOI: 10.1021/acsinfecdis.9b00245 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.21 Å) |
Structure validation
Download full validation report