6PLK

Crystal structure of ZIKV-116 Fab in complex with ZIKV envelope DIII

6PLK の概要

• エントリーDOI: 10.2210/pdb6plk/pdb
• 分子名称: ZIKV-116 heavy chain, ZIKV-116 light chain, Env, ... (4 entities in total)
• 機能のキーワード: human antibody, zikv-diii, antiviral protein, structural genomics, center for structural genomics of infectious diseases, csgid
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 118949.84

構造登録者

Zhao, H.,Fremont, D.H.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2019-07-01, 公開日: 2019-11-20, 最終更新日: 2023-10-11)

• 主引用文献: Zhao, H.,Xu, L.,Bombardi, R.,Nargi, R.,Deng, Z.,Errico, J.M.,Nelson, C.A.,Dowd, K.A.,Pierson, T.C.,Crowe, J.E.,Diamond, M.S.,Fremont, D.H.; Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge.; J.Exp.Med., 217:-, 2020; PubMed: 31757867; DOI: 10.1084/jem.20191792

実験手法

X-RAY DIFFRACTION (2.3 Å)