6PLA

Adducts formed after 1 month in the reaction of dichlorido(1,3-dimethylbenzimidazol-2-ylidene)(eta6-p-cymene)osmium(II) with HEWL

Summary for 6PLA

Entry DOI	10.2210/pdb6pla/pdb
Descriptor	Lysozyme, SODIUM ION, dichlorido(1,3-dimethylbenzimidazol-2-ylidene)(eta6-p-cymene)osmium(II), ... (5 entities in total)
Functional Keywords	metal-based, anticancer, ruthenium, nhc, carbene, lysozyme, metallodrug, benzimidazole, dimethylbenzimidazole, hydrolase
Biological source	Gallus gallus (Chicken)
Total number of polymer chains	1
Total formula weight	15619.40
Authors	Sullivan, M.P.,Hartinger, C.G.,Goldstone, D.C. (deposition date: 2019-06-30, release date: 2020-11-25, Last modification date: 2023-10-11)
Primary citation	Sullivan, M.P.,Cziferszky, M.,Tolbatov, I.,Truong, D.,Mercadante, D.,Re, N.,Gust, R.,Goldstone, D.C.,Hartinger, C. Probing the Paradigm of Promiscuity for N-Heterocyclic Carbene Complexes and their Protein Adduct Formation. Angew.Chem.Int.Ed.Engl., 2021 Cited by PubMed: 34196088 DOI: 10.1002/anie.202106906 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.25 Å)

Structure validation