6PL2

TRK-A IN COMPLEX WITH LIGAND 1a

Summary for 6PL2

Entry DOI	10.2210/pdb6pl2/pdb
Descriptor	High affinity nerve growth factor receptor, N-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)-2-{[1-(4-hydroxyphenyl)-1H-tetrazol-5-yl]sulfanyl}acetamide (3 entities in total)
Functional Keywords	trk-a kinase domain, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	35878.25
Authors	Subramanian, G. (deposition date: 2019-06-30, release date: 2019-09-04, Last modification date: 2019-09-25)
Primary citation	Subramanian, G.,Bowen, S.J.,Zhu, Y.,Roush, N.,Zachary, T.,Javens, C.,Williams, T.,Janssen, A.,Gonzales, A. Type 2 inhibitor leads of human tropomyosin receptor kinase (hTrkA). Bioorg.Med.Chem.Lett., 29:126624-126624, 2019 Cited by PubMed: 31444087 DOI: 10.1016/j.bmcl.2019.126624 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.59 Å)

Structure validation