6PEZ

SOLID-STATE NMR STRUCTURE OF PISCIDIN 3 IN ALIGNED 4:1 PHOSPHATIDYLCHOLINE/CHOLESTEROL LIPID BILAYERS

Summary for 6PEZ

• Entry DOI: 10.2210/pdb6pez/pdb
• NMR Information: BMRB: 30615
• Descriptor: Piscidin-3 (1 entity in total)
• Functional Keywords: antimicrobial peptide, anticancer peptide, anti hiv-1, cationic, amphipathic, histidine rich, helical, lipid bilayers, bacterial cell membrane mimic, antimicrobial protein
• Biological source: Morone chrysops x Morone saxatilis (White bass x Striped bass)
• Total number of polymer chains: 1
• Total formula weight: 2495.95

Authors

Greenwood, A.I.,Cairns, L.S.,Fu, R.,Cotten, M.L. (deposition date: 2019-06-21, release date: 2019-10-16, Last modification date: 2023-06-14)

• Primary citation: Comert, F.,Greenwood, A.,Maramba, J.,Acevedo, R.,Lucas, L.,Kulasinghe, T.,Cairns, L.S.,Wen, Y.,Fu, R.,Hammer, J.,Blazyk, J.,Sukharev, S.,Cotten, M.L.,Mihailescu, M.; The host-defense peptide piscidin P1 reorganizes lipid domains in membranes and decreases activation energies in mechanosensitive ion channels.; J.Biol.Chem., 294:18557-18570, 2019; PubMed: 31619519; DOI: 10.1074/jbc.RA119.010232

Experimental method

SOLID-STATE NMR