6PEQ

GluA2 in complex with its auxiliary subunit CNIH3 - map LBD-TMD-C3 - with antagonist ZK200775 -without NTD

Summary for 6PEQ

Entry DOI	10.2210/pdb6peq/pdb
EMDB information	20330 20654 20666
Descriptor	Glutamate receptor 2, Protein cornichon homolog 3, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid, ... (6 entities in total)
Functional Keywords	ionotropic glutamate receptor, ampa receptor, cornichon, auxiliary subunit, ion channel, ligand gated ion channel, synaptic transmission, excitatory synaptic transmission, neurotransmitter receptor, stargazin, tarp, zk200775, lipid, mpqx, transport protein
Biological source	Rattus norvegicus (Rat) More
Total number of polymer chains	8
Total formula weight	488770.26
Authors	Nakagawa, T. (deposition date: 2019-06-20, release date: 2019-12-04, Last modification date: 2019-12-18)
Primary citation	Nakagawa, T. Structures of the AMPA receptor in complex with its auxiliary subunit cornichon. Science, 366:1259-1263, 2019 Cited by PubMed: 31806817 DOI: 10.1126/science.aay2783 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.97 Å)

Structure validation