6PE9

Crystal Structure of CD40 complexed to FAB516

Summary for 6PE9

• Entry DOI: 10.2210/pdb6pe9/pdb
• Descriptor: FAB Heavy chain, FAB Light chain, Tumor necrosis factor receptor superfamily member 5, ... (5 entities in total)
• Functional Keywords: cd40, fab, complex, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 15
• Total formula weight: 336555.13

Authors

Argiriadi, M.A. (deposition date: 2019-06-20, release date: 2019-08-14, Last modification date: 2023-10-11)

• Primary citation: Argiriadi, M.A.,Benatuil, L.,Dubrovska, I.,Egan, D.A.,Gao, L.,Greischar, A.,Hardman, J.,Harlan, J.,Iyer, R.B.,Judge, R.A.,Lake, M.,Perron, D.C.,Sadhukhan, R.,Sielaff, B.,Sousa, S.,Wang, R.,McRae, B.L.; CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches.; BMC Mol Cell Biol, 20:29-29, 2019; PubMed: 31382872; DOI: 10.1186/s12860-019-0213-4

Experimental method

X-RAY DIFFRACTION (3.13 Å)