6PE8
Crystal structure of CD40/ABBV-323 FAB complex
Summary for 6PE8
Entry DOI | 10.2210/pdb6pe8/pdb |
Descriptor | FAB Heavy chain, FAB Light chain, Tumor necrosis factor receptor superfamily member 5, ... (5 entities in total) |
Functional Keywords | cd40, fab, complex, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 134838.25 |
Authors | Argiriadi, M.A. (deposition date: 2019-06-20, release date: 2019-08-14, Last modification date: 2023-10-11) |
Primary citation | Argiriadi, M.A.,Benatuil, L.,Dubrovska, I.,Egan, D.A.,Gao, L.,Greischar, A.,Hardman, J.,Harlan, J.,Iyer, R.B.,Judge, R.A.,Lake, M.,Perron, D.C.,Sadhukhan, R.,Sielaff, B.,Sousa, S.,Wang, R.,McRae, B.L. CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches. BMC Mol Cell Biol, 20:29-29, 2019 Cited by PubMed: 31382872DOI: 10.1186/s12860-019-0213-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.84 Å) |
Structure validation
Download full validation report