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6PC8

E. coli 50S ribosome bound to compound 40q

Summary for 6PC8
Entry DOI10.2210/pdb6pc8/pdb
EMDB information20299
Descriptor23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ... (8 entities in total)
Functional Keywordse. coli ribosome, streptogramin a analog, antibiotics, ribosome
Biological sourceEscherichia coli
More
Total number of polymer chains7
Total formula weight1085808.52
Authors
Pellegrino, J.,Lee, D.J.,Fraser, J.S.,Seiple, I.B. (deposition date: 2019-06-16, release date: 2020-06-17, Last modification date: 2020-10-07)
Primary citationLi, Q.,Pellegrino, J.,Lee, D.J.,Tran, A.A.,Chaires, H.A.,Wang, R.,Park, J.E.,Ji, K.,Chow, D.,Zhang, N.,Brilot, A.F.,Biel, J.T.,van Zundert, G.,Borrelli, K.,Shinabarger, D.,Wolfe, C.,Murray, B.,Jacobson, M.P.,Muhle, E.,Chesneau, O.,Fraser, J.S.,Seiple, I.B.
Synthetic group A streptogramin antibiotics that overcome Vat resistance.
Nature, 586:145-150, 2020
Cited by
PubMed: 32968273
DOI: 10.1038/s41586-020-2761-3
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (2.9 Å)
Structure validation

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