6P97

OXA-48 carbapanemase, imipenem complex

Summary for 6P97

• Entry DOI: 10.2210/pdb6p97/pdb
• Descriptor: Beta-lactamase, (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carboxylic acid, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: antibiotic resistance, beta-lactamase, carbapenemase, imipenem complex, hydrolase
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 2
• Total formula weight: 61923.11

Authors

Smith, C.A.,Vakulenko, S.B. (deposition date: 2019-06-10, release date: 2019-08-07, Last modification date: 2019-10-09)

• Primary citation: Smith, C.A.,Stewart, N.K.,Toth, M.,Vakulenko, S.B.; Structural Insights into the Mechanism of Carbapenemase Activity of the OXA-48 beta-Lactamase.; Antimicrob.Agents Chemother., 63:-, 2019; PubMed: 31358584; DOI: 10.1128/AAC.01202-19

Experimental method

X-RAY DIFFRACTION (1.8 Å)