6P94

Human APE1 C65A AP-endonuclease product complex

Summary for 6P94

• Entry DOI: 10.2210/pdb6p94/pdb
• Related: 6P93
• Descriptor: DNA-(apurinic or apyrimidinic site) lyase, DNA (5'-D(P*(3DR)P*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), ... (9 entities in total)
• Functional Keywords: ape1, nuclease, dna repair, dna binding protein, lyase-dna complex, lyase/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 75463.36

Authors

Whitaker, A.W.,Stark, W.J.,Freudenthal, B.D. (deposition date: 2019-06-09, release date: 2020-01-01, Last modification date: 2023-10-11)

• Primary citation: McNeill, D.R.,Whitaker, A.M.,Stark, W.J.,Illuzzi, J.L.,McKinnon, P.J.,Freudenthal, B.D.,Wilson, D.M.; Functions of the major abasic endonuclease (APE1) in cell viability and genotoxin resistance.; Mutagenesis, 35:27-38, 2020; PubMed: 31816044; DOI: 10.1093/mutage/gez046

Experimental method

X-RAY DIFFRACTION (2.09 Å)