6P69

Crystal structure of FGFR1-Y563C (FGFR4 surrogate) covalently bound to compound 11.

Summary for 6P69

• Entry DOI: 10.2210/pdb6p69/pdb
• Related: 6P68
• Descriptor: Fibroblast growth factor receptor 1, SULFATE ION, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: fgfr, inhibitor complex, covalent inhibitor, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 71912.14

Authors

Larsen, N.A. (deposition date: 2019-06-03, release date: 2019-06-19, Last modification date: 2023-10-11)

• Primary citation: Prajapati, S.; To be published; TBD,

Experimental method

X-RAY DIFFRACTION (2.2 Å)