6P3Q

Calpain-5 (CAPN5) Protease Core (PC)

Summary for 6P3Q

Entry DOI	10.2210/pdb6p3q/pdb
Descriptor	Calpain-5 (1 entity in total)
Functional Keywords	cystein protease, peptide binding protein, calcium binding protein, protease domain, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	82733.20
Authors	Velez, G.,Sun, Y.J.,Khan, S.,Yang, J.,Koster, H.J.,Lokesh, G.,Mahajan, V. (deposition date: 2019-05-24, release date: 2020-02-05, Last modification date: 2024-04-03)
Primary citation	Velez, G.,Sun, Y.J.,Khan, S.,Yang, J.,Herrmann, J.,Chemudupati, T.,MacLaren, R.E.,Gakhar, L.,Wakatsuki, S.,Bassuk, A.G.,Mahajan, V.B. Structural Insights into the Unique Activation Mechanisms of a Non-classical Calpain and Its Disease-Causing Variants. Cell Rep, 30:881-892.e5, 2020 Cited by PubMed: 31968260 DOI: 10.1016/j.celrep.2019.12.077 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation