6P0Z

Crystal structure of N-acetylated KRAS (2-169) bound to GDP and Mg

Summary for 6P0Z

• Entry DOI: 10.2210/pdb6p0z/pdb
• Descriptor: GTPase KRas, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... (6 entities in total)
• Functional Keywords: kras, ras, mg, k-ras, small gtpase, guanine nucleotide, oncoprotein, gmppnp, gppnhp
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 39410.36

Authors

Dharmaiah, S.,Tran, T.H.,Yan, W.,Simanshu, D.K. (deposition date: 2019-05-17, release date: 2019-07-31, Last modification date: 2023-10-11)

• Primary citation: Dharmaiah, S.,Tran, T.H.,Messing, S.,Agamasu, C.,Gillette, W.K.,Yan, W.,Waybright, T.,Alexander, P.,Esposito, D.,Nissley, D.V.,McCormick, F.,Stephen, A.G.,Simanshu, D.K.; Structures of N-terminally processed KRAS provide insight into the role of N-acetylation.; Sci Rep, 9:10512-10512, 2019; PubMed: 31324887; DOI: 10.1038/s41598-019-46846-w

Experimental method

X-RAY DIFFRACTION (1.011 Å)