6P0R
Methyltransferase domain of human suppressor of variegation 3-9 homolog 2 (SUV39H2) in complex with OTS186935 inhibitor
6P0R の概要
エントリーDOI | 10.2210/pdb6p0r/pdb |
分子名称 | Histone-lysine N-methyltransferase SUV39H2, (3S)-1-[2-(5-chloro-2,4-dimethoxyphenyl)imidazo[1,2-a]pyridin-7-yl]-N-[(pyridin-4-yl)methyl]pyrrolidin-3-amine, ZINC ION, ... (5 entities in total) |
機能のキーワード | methyltransferase domain, suv39h2, ots186935, structural genomics, structural genomics consortium, sgc, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
由来する生物種 | Homo sapiens (Human) |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 69363.58 |
構造登録者 | Halabelian, L.,Dong, A.,Zeng, H.,Loppnau, P.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Brown, P.J.,Structural Genomics Consortium (SGC) (登録日: 2019-05-17, 公開日: 2019-05-29, 最終更新日: 2023-10-11) |
主引用文献 | Halabelian, L.,Dong, A.,Zeng, H.,Loppnau, P.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Brown, P.J.,Structural Genomics Consortium (SGC) Methyltransferase domain of human suppressor of variegation 3-9 homolog 2 (SUV39H2) in complex with OTS186935 inhibitor to be published, |
実験手法 | X-RAY DIFFRACTION (2.4 Å) |
構造検証レポート
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