6OXH

X-ray crystal structure of His-tagged Y140F FtmOx1 bound to Fe(II) and 2-oxoglutarate

6OXH の概要

• エントリーDOI: 10.2210/pdb6oxh/pdb
• 分子名称: Verruculogen synthase, FE (II) ION, 2-OXOGLUTARIC ACID, ... (4 entities in total)
• 機能のキーワード: endoperoxidation, deprenylation, oxygenase, metalloenzyme, fumitremorgin, verruculogen, oxidoreductase
• 由来する生物種: Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus Af293)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 70610.23

構造登録者

Dunham, N.P.,Boal, A.K. (登録日: 2019-05-13, 公開日: 2019-07-03, 最終更新日: 2023-10-11)

• 主引用文献: Dunham, N.P.,Del Rio Pantoja, J.M.,Zhang, B.,Rajakovich, L.J.,Allen, B.D.,Krebs, C.,Boal, A.K.,Bollinger Jr., J.M.; Hydrogen Donation but not Abstraction by a Tyrosine (Y68) during Endoperoxide Installation by Verruculogen Synthase (FtmOx1).; J.Am.Chem.Soc., 141:9964-9979, 2019; PubMed: 31117657; DOI: 10.1021/jacs.9b03567

実験手法

X-RAY DIFFRACTION (1.92 Å)