6OWJ

Zn-mediated polymerization of human SFPQ

Summary for 6OWJ

• Entry DOI: 10.2210/pdb6owj/pdb
• Descriptor: Splicing factor, proline- and glutamine-rich, ZINC ION (3 entities in total)
• Functional Keywords: sfpq, dbhs protein, rrm, zn, polymerization, nuclear protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 60253.50

Authors

Lee, M. (deposition date: 2019-05-10, release date: 2020-02-05, Last modification date: 2023-10-11)

• Primary citation: Huang, J.,Ringuet, M.,Whitten, A.E.,Caria, S.,Lim, Y.W.,Badhan, R.,Anggono, V.,Lee, M.; Structural basis of the zinc-induced cytoplasmic aggregation of the RNA-binding protein SFPQ.; Nucleic Acids Res., 48:3356-3365, 2020; PubMed: 32034402; DOI: 10.1093/nar/gkaa076

Experimental method

X-RAY DIFFRACTION (1.94 Å)