6OTS

Rat ERK2 E320K

Summary for 6OTS

• Entry DOI: 10.2210/pdb6ots/pdb
• Descriptor: Mitogen-activated protein kinase 1 (2 entities in total)
• Functional Keywords: kinase, mapk, erk, cancer, transferase
• Biological source: Rattus norvegicus (Rat)
• Total number of polymer chains: 1
• Total formula weight: 41330.62

Authors

Taylor, C.A.,Cormier, K.W.,Juang, Y.-C.,Goldsmith, E.J.,Cobb, M.H. (deposition date: 2019-05-03, release date: 2019-07-10, Last modification date: 2023-10-11)

• Primary citation: Taylor 4th, C.A.,Cormier, K.W.,Keenan, S.E.,Earnest, S.,Stippec, S.,Wichaidit, C.,Juang, Y.C.,Wang, J.,Shvartsman, S.Y.,Goldsmith, E.J.,Cobb, M.H.; Functional divergence caused by mutations in an energetic hotspot in ERK2.; Proc.Natl.Acad.Sci.USA, 116:15514-15523, 2019; PubMed: 31296562; DOI: 10.1073/pnas.1905015116

Experimental method

X-RAY DIFFRACTION (2.1 Å)