6OTD

Globin sensor domain of AfGcHK in monomeric form, with imidazole

Summary for 6OTD

• Entry DOI: 10.2210/pdb6otd/pdb
• Related: 5OHE 5OHF
• Descriptor: Globin-coupled histidine kinase, PROTOPORPHYRIN IX CONTAINING FE, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (5 entities in total)
• Functional Keywords: heme, sensor protein, oxygen sensor, globin sensor domain, globin domain, transferase, imidazole
• Biological source: Anaeromyxobacter sp. Fw109-5
• Total number of polymer chains: 1
• Total formula weight: 19243.69

Authors

Skalova, T.,Dohnalek, J.,Kolenko, P.,Stranava, M.,Lengalova, A.,Martinkova, M. (deposition date: 2019-05-03, release date: 2020-01-08, Last modification date: 2023-10-11)

• Primary citation: Skalova, T.,Lengalova, A.,Dohnalek, J.,Harlos, K.,Mihalcin, P.,Kolenko, P.,Stranava, M.,Blaha, J.,Shimizu, T.,Martinkova, M.; Disruption of the dimerization interface of the sensing domain in the dimeric heme-based oxygen sensorAfGcHK abolishes bacterial signal transduction.; J.Biol.Chem., 295:1587-1597, 2020; PubMed: 31914416; DOI: 10.1074/jbc.RA119.011574

Experimental method

X-RAY DIFFRACTION (1.8 Å)