6OPN
CD4- and 17-bound HIV-1 Env B41 SOSIP in complex with small molecule GO35
Summary for 6OPN
Entry DOI | 10.2210/pdb6opn/pdb |
EMDB information | 20150 |
Descriptor | Envelope glycoprotein gp160, Envelope glycoprotein gp41, T-cell surface glycoprotein CD4, ... (7 entities in total) |
Functional Keywords | hiv-1, env, cd4, receptor-bound state, small molecule, fusion inhibitor, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 9 |
Total formula weight | 308830.21 |
Authors | Ozorowski, G.,Torres, J.L.,Ward, A.B. (deposition date: 2019-04-25, release date: 2020-10-21, Last modification date: 2020-12-09) |
Primary citation | Ozorowski, G.,Torres, J.L.,Santos-Martins, D.,Forli, S.,Ward, A.B. A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide. Cell Rep, 33:108428-108428, 2020 Cited by PubMed: 33238117DOI: 10.1016/j.celrep.2020.108428 PDB entries with the same primary citation |
Experimental method |
Structure validation
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