6OOJ

CTX-M-14 Beta Lactamase with Compound 14

Summary for 6OOJ

• Entry DOI: 10.2210/pdb6ooj/pdb
• Descriptor: Beta-lactamase, 3-(1H-pyrazol-1-yl)-N-[3-(1H-tetrazol-5-yl)phenyl]-5-(trifluoromethyl)benzamide (3 entities in total)
• Functional Keywords: beta-lactamase, esbl, non covalent complex, hydrolase, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 57564.35

Authors

Kemp, M.,Chen, Y. (deposition date: 2019-04-23, release date: 2020-07-01, Last modification date: 2023-10-11)

• Primary citation: DeFrees, K.,Kemp, M.T.,ElHilali-Pollard, X.,Zhang, X.,Mohamed, A.,Chen, Y.,Renslo, A.R.; An Empirical Study of Amide-Heteroarene pi-Stacking Interactions Using Reversible Inhibitors of a Bacterial Serine Hydrolase.; Org Chem Front, 6:1749-1756, 2019; PubMed: 32774871; DOI: 10.1039/c9qo00342h

Experimental method

X-RAY DIFFRACTION (1.4 Å)