6OOA

Human CYP3A4 bound to a drug substrate

Summary for 6OOA

Entry DOI	10.2210/pdb6ooa/pdb
Descriptor	Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, GLYCEROL, ... (5 entities in total)
Functional Keywords	substrate, complex, oxidoreductase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	56945.04
Authors	Sevrioukova, I.F. (deposition date: 2019-04-22, release date: 2019-09-11, Last modification date: 2023-10-11)
Primary citation	Sevrioukova, I.F. Structural Insights into the Interaction of Cytochrome P450 3A4 with Suicide Substrates: Mibefradil, Azamulin and 6',7'-Dihydroxybergamottin. Int J Mol Sci, 20:-, 2019 Cited by PubMed: 31480231 DOI: 10.3390/ijms20174245 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.52 Å)

Structure validation